Rsv Research Paper

Rsv Research Paper-56
The outsides of these nanoparticles were fitted with inert RSV proteins to create the vaccine.Those RSV proteins are prefusion-stabilized variants of the F glycoprotein trimer developed at the National Institute for Allergy and Infectious Disease Vaccine Research Center at the National Institutes of Health.In the United States, RSV is the leading cause of pneumonia in babies under a year old.

The outsides of these nanoparticles were fitted with inert RSV proteins to create the vaccine.Those RSV proteins are prefusion-stabilized variants of the F glycoprotein trimer developed at the National Institute for Allergy and Infectious Disease Vaccine Research Center at the National Institutes of Health.In the United States, RSV is the leading cause of pneumonia in babies under a year old.

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The project was funded primarily by the Bill and Melinda Gates Foundation, and also by the state of Washington, the Howard Hughes Medical Institute, the Netherlands Organization for Scientific Research, the European Molecular Biology Organisation, the Swedish Research Council, Karolinska Institutet, National Institute of Allergy and Infectious Diseases, National Institute for General Medical Sciences, a Pew Biomedical Scholars Award, and an Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund.

Introduction The melamine controversy that erupted during the last quarter of year 2008 brought people’s attention back to the debates between breastfeeding and the use of breast milk substitutes like commercial infant formula.

"We will continue to develop this technology so that we and others can make new vaccines better, cheaper, and faster.

We are excited to work with our many partners and collaborators to translate our work in the lab into actual vaccines that go out into the world and, hopefully, save lives." The RSV vaccine team was led by researchers at UW Medicine and the Institute for Research in Biomedicine in Bellinzona, Switzerland.

RSV infects nearly all children by the age of three.

Infection typically causes mild symptoms, but can be more serious in newborns, immunocompromised individuals and the elderly.

Their use in this study is part of a larger trend called structure-based vaccine design. Using computationally designed protein nanoparticles, however, allows for much more control over important vaccine properties, such as overall size, stability, and the number of antigens presented to the immune system.

Recently, scientists have repurposed natural nanoparticles to create experimental vaccines for HIV, hepatitis C, and other diseases, according to a Feb. "This is the first of many vaccine candidates we have made using this technology," said senior author Neil King, assistant professor of biochemistry at the UW School of Medicine.

This finding suggests it may translate into a more effective vaccine with more durable protection.

Nanoparticles are already known to give vaccines a boost.

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